The following files, in tab-delimited-text format, contain the information that is displayed in graphical format in the Arachidonic Acid Pathway figure shown at http://pentaconhq.princeton.edu/?q=pathways .

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File 1:
AAP_figure_Category_names_20131202_production.txt

This file contains the names, numbers, and captions for the 58 categories of elements (proteins, eicosanoids, and COX inhibitors) shown in the figure.  Note that the category numbers are not consecutive; categories 1-30 are for proteins (except for category 6, "diet"), and 100-127 are for chemical entities.  The file contains 1 header row and 3 columns.  Columns 2 and 3 contain some entries with HTML tags.  The columns are:

	1: Category #
	2: Category name
	3: Caption (if any)

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File 2:
AAP_figure_Protein_names_20131202_production.txt

This file contains the UniProt IDs and recommended display names for the proteins shown in the figure.  It contains 1 header row and 2 columns.  The columns are:

	1: UniProt ID
	2: Recommended name

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File 3:
AAP_figure_Protein_categories_20131202_production.txt

Genes/proteins are assigned to the categories from file 1.  This file contains 1 header row and 34 columns.  The columns are:

	1: Gene name
	2: UniProt ID
	3: NCBI ID
	4: EC# (optional)
	5-33: Categories 1-5 and 7-30, listed by number
	34: Notes

In columns 5-33, genes are classified as "D," "I," or "P" for "direct," "indirect," and "predicted" as follows:

	Direct: Experimental evidence demonstrates that these human proteins have the indicated roles or activities.

	Indirect: These human proteins are likely to have the indicated role or activity based on experimental evidence using a relevant substrate, but not necessarily the specified canonical substrate.  For example, an enzyme known to act on palmitic, oleic, or linoleic acid may be inferred to be involved in arachidonic acid remodeling.

	Predicted: These proteins have been inferred to have the indicated role based only on homology or evidence from other organisms.

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File 4:
AAP_figure_COX_inhibitors_20131202_production.txt

This file contains the names and PharmGKB IDs for COX inhibitors, which are also assigned to the categories "Non-selective NSAIDs" (category 101) or "COX2 inhibitors" (category 102).  This file contains 1 header row and 4 columns.  Columns:

	1: Name
	2: Non-selective NSAIDs
	3: COX2 inhibitors
	4: PharmGKB ID (when available)

Key to columns 2 & 3:

	x = assigned to that category
	s = slightly COX2-selective

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File 5:
AAP_figure_Eicosanoids_20131202_production.txt

This file contains the names and ChEBI IDs of eicosanoids, metabolites, intermediates, and other chemicals assigned to categories from file 1.  The file contains 1 header row and 30 columns.  Columns:

	1: ChEBI ASCII Name (plaintext)
	2: ChEBI ASCII Name (with HTML)
	3: Reference
	4: ChEBI ID
	5-30: Categories 100 (arachidonic acid) and 103-127

(Categories 101 and 102 are for COX inhibitors.)

As in file 4, x's denote assignment to categories.  Column 3, "Reference,"  broadly identifies the source of the information.